complications of gold sodium thiomalate therapy in rheumatoid arthritis
نویسندگان
چکیده
to determine the complications of gold sodium thiomalate therapy in rheumatoid arthritis (ra), 32 patients with active ra (27 female, 5 male) treated for a mean period of 28 ? 14 weeks were studied. from these patients, 62.5 (46-79) percent showed at least one drug reaction. pruritus was the most common complication occurred in 59 (42-76) percents, and was accompanied by skin rush in 37 (15-57) percents of cases. renal, mucosal and post-injection complication developed, each in 16 (3-29) and percents of patients. hematologic and pulmonary reaction occurred in 12.5 (1-24) and 9 (1-19) percents of cases respectively. drug reaction resulted to discontinuation of gold therapy in 19 (5-32) percents of patients. majority of drug reactions occurred during the first 15 weeks of therapy. in comparison to reports coming from other studies, drug reactions in iranian patients were more frequent but less severe.
منابع مشابه
ADVERSE REACTIONS OF GOLD SODIUM THIOMALATE IN RHEUMATOID ARTHRI TIS PATIENTS IN SOUTHERN IRAN
To confirm the side-effects of gold sodium thiomalate (GSTM), we carried out a retrospective study examining 102 consecutive patients with rheumatoid arthritis attending the Rheumatology Unit of Hafez Hospital, Shiraz, Iran, in whom GSTM was initiated between 1983-1989. Only patients with classical or definite RA (ARA criteria) we(e included in this study. Patients were categorized as havi...
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متن کاملadverse reactions of gold sodium thiomalate in rheumatoid arthri tis patients in southern iran
to confirm the side-effects of gold sodium thiomalate (gstm), we carried out a retrospective study examining 102 consecutive patients with rheumatoid arthritis attending the rheumatology unit of hafez hospital, shiraz, iran, in whom gstm was initiated between 1983-1989. only patients with classical or definite ra (ara criteria) we(e included in this study. patients were categorized as having de...
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عنوان ژورنال:
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهرانجلد ۵۹، شماره ۱، صفحات ۸۱-۸۵
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